The 180 gr premium boat tail hunting bullet is the way to go on this round. You can get 3200+ fps, which gives it a good trajectory out to almost 400 yards, and a lot of long range horsepower. The ONLY reason to have this caliber is for shots OVER 300 yards.
IMR 7828, Alliant RL-25 or Hodgdon H1000 is going to be hard to beat.
Nosler's 180 gr Ballistic Tip is a very accurate hunting bullet. For big game that can bite back and MUST be anchored immediately, use the 180 Nosler Partition. Forget lighter bullets. At long range, the heavier bullet will outperform them.
Use ONLY the Fed 215 or Fed 215M. This primer was designed for the Weatherby Mags.
This is not a plinker. Without a brake, it will ring your bell. With a brake, use muffs AND plugs, and let others on the range know it is time to gear up.
The 26" barrel makes the 300 roar.