The Dillon 650 with the optional casefeeder can be outfitted with a P/W autodrive and a Double Alpha bullet feeder. By pushing a toggle switch and pressing a button, you'll be cranking out quality 800 rifle to 1000 pistol reloads an hour. Your only bottleneck is the primer system; but as long as you have several tubes pre-filled, you're good to go. It's as close to full automation as you can get without investing in commercial types machines. Total cost: around $2500.
Having quality dies such as the one being offered here also helps.
The only downside is you better have a lot of components ready as you'll go through them quickly.